Dr Per Sjöberg from the Department of Physical and Analytical Chemistry at Uppsala University in Sweden has demonstrated that electrochemistry (EC) coupled to liquid chromatography (LC) and electrospray ionization tandem mass spectrometry (LC/EC/ESI-MS/MS) can be used to rapidly obtain information about the antioxidant activity
Dr Bart van der Bruggen and a team from the Department of Chemical Engineering, KU Leuven and PerkinElmer, Belgium, employed static headspace gas chromatography coupled to mass spectrometry (SHGC–MS) to identify aroma compounds in coffee pad powder.
Professor Wolf Lehmann, from Molecular Structure Analysis at the German Cancer Research Center (DKFZ) Heidelberg, Germany, conducted a study to characterize in detail the in vitro phosphorylation of the recombinant Plasmodium falciparum protein GAP45 by a kinase from the same organism.
The current use of cystoscopy for screening and detecting bladder cancer is invasive and expansive. Various urine-based biomarkers have been used for this purpose with limited success.
Twelve chiral derivatizing reagents (CDRs) were synthesized by substituting one of the fluorine atoms in 1,5-difluoro-2,4-dinitrobenzene (DFDNB) with three optically pure amines [(R)-(-)-1-cyclohexylethylamine, (+)-dehydroabietylamine and (S)-(-)- ,4-dimethylbenzylamine], six amino acid amides [L-Ala-NH2, L-Phe-NH2, L-Val-NH2, L-Leu-NH2, L-Met-NH2 and D-Phg-NH2] and three amino acids [L-Ala, L-Val and L-Leu]. The work was led by Professor Ravi Bhushan from the Department of Chemistry at the Indian Institute of Technology Roorkee in India and documented in Biomedical Chromatography [23 (12) 1291 – 1299 (2009)].